C3orf37 antibody (N-Term)

Catalog No. ABIN5518008

This Rabbit Polyclonal antibody specifically detects C3orf37 in WB. It exhibits reactivity toward Human, Mouse, Rabbit, Cow, Dog, Horse, Pig, Rat and Zebrafish (Danio rerio).

Quick Overview for C3orf37 antibody (N-Term) (ABIN5518008)

Target: C3orf37 (C3ORF37) (Chromosome 3 Open Reading Frame 37 (C3ORF37))

Reactivity: Human, Mouse, Rabbit, Cow, Dog, Horse, Pig, Rat, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C3orf37 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-C3orf37 Antibody

Binding Specificity: N-Term

Purpose: HMCES Antibody - N-terminal region

Sequence: GQQRLPEWRD PDKYCPSYNK SPQSNSPVLL SRLHFEKDAD SSERIIAPMR

Predicted Reactivity: Cow: 85%, Dog: 92%, Horse: 85%, Human: 100%, Mouse: 92%, Pig: 77%, Rabbit: 92%, Rat: 92%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against HMCES. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human HMCES

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP57365-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for C3orf37

Target: C3orf37 (C3ORF37) (Chromosome 3 Open Reading Frame 37 (C3ORF37))

Alternative Name: HMCES

Background:

Background Information: HMCES specifically binds 5-hydroxymethylcytosine (5hmC)- containing DNA in stem cells, suggesting that it acts as a specific reader of 5hmC in stem cells (By similarity). IT may act as a peptidase, experimental evidences are however required to confirm this prediction.

Gene Name: chromosome 3 open reading frame 37

Alternative Symbols: DC12, SRAPD1, C3orf37

Protein Name: UPF0361 protein C3orf37

Molecular Weight: 38kDa

Gene ID: 56941

NCBI Accession: XP_005247693

UniProt: Q96FZ2