ALDH1A1 antibody (N-Term)

Catalog No. ABIN5518032

This Rabbit Polyclonal antibody specifically detects ALDH1A1 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Guinea Pig, Rabbit, Sheep, Dog, Horse, Pig and Zebrafish (Danio rerio).

Quick Overview for ALDH1A1 antibody (N-Term) (ABIN5518032)

Target: ALDH1A1 (Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1))

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Rabbit, Sheep, Dog, Horse, Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ALDH1A1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ALDH1A1 Antibody

Binding Specificity: N-Term

Sequence: PDLPVLLTDL KIQYTKIFIN NEWHDSVSGK KFPVFNPATE EELCQVEEGD

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 92%, Pig: 100%, Rabbit: 86%, Rat: 92%, Sheep: 100%, Zebrafish: 82%

Characteristics: This is a rabbit polyclonal antibody against ALDH1A1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of human ALDH1A1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ALDH1A1

Target: ALDH1A1 (Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1))

Alternative Name: ALDH1A1

Background: The protein encoded by this gene belongs to the aldehyde dehydrogenase family. Aldehyde dehydrogenase is the next enzyme after alcohol dehydrogenase in the major pathway of alcohol metabolism. There are two major aldehyde dehydrogenase isozymes in the liver, cytosolic and mitochondrial, which are encoded by distinct genes, and can be distinguished by their electrophoretic mobility, kinetic properties, and subcellular localization. This gene encodes the cytosolic isozyme. Studies in mice show that through its role in retinol metabolism, this gene may also be involved in the regulation of the metabolic responses to high-fat diet.

Alias Symbols: ALDC, ALDH1, HEL-9, HEL12, PUMB1, ALDH11, RALDH1, ALDH-E1, HEL-S-53e

Protein Size: 230

Gene ID: 216

NCBI Accession: NM_000689, NP_000680

UniProt: P00352

Pathways: Dopaminergic Neurogenesis