H2BFWT antibody (N-Term)

Catalog No. ABIN5518047

This Rabbit Polyclonal antibody specifically detects H2BFWT in WB. It exhibits reactivity toward Human.

Quick Overview for H2BFWT antibody (N-Term) (ABIN5518047)

Target: H2BFWT (H2B Histone Family, Member W, Testis-Specific (H2BFWT))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This H2BFWT antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-H2BFWT Antibody

Binding Specificity: N-Term

Purpose: H2BFWT Antibody - N-terminal region

Sequence: MAGPSSETTS EEQLITQEPK EANSTTSQKQ SKQRKRGRHG PRRCHSNCRG

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against H2BFWT. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human H2BFWT

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP73455-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for H2BFWT

Target: H2BFWT (H2B Histone Family, Member W, Testis-Specific (H2BFWT))

Alternative Name: H2BFWT

Background:

Background Information: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a member of the H2B histone family that is specifically expressed in sperm nuclei. A polymorphism in the 5' UTR of this gene is associated with male infertility.

Alternative Symbols: H2BFWT

Molecular Weight: 19kDa

Gene ID: 158983

NCBI Accession: NP_001002916

UniProt: Q7Z2G1