C11ORF80 antibody (C-Term)

Catalog No. ABIN5518072

The Rabbit Polyclonal anti-C11ORF80 antibody is suitable to detect C11ORF80 in samples from Human. It has been validated for WB.

Quick Overview for C11ORF80 antibody (C-Term) (ABIN5518072)

Target: C11ORF80 (Chromosome 11 Open Reading Frame 80 (C11ORF80))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C11ORF80 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-C11ORF80 Antibody

Binding Specificity: C-Term

Purpose: C11ORF80 Antibody - C-terminal region

Sequence: KVFREITQHQ FLHHCSCEVK QLTLEKKDSA QGTEDAPDNS SLELLADTSG

Predicted Reactivity: Human: 100%, Rat: 83%

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human C11ORF80

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP68096-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for C11ORF80

Target: C11ORF80 (Chromosome 11 Open Reading Frame 80 (C11ORF80))

Alternative Name: C11ORF80

Background:

Background Information: Isoform 3: Component of a topoisomerase 6 complex specifically required for meiotic recombination. Together with SPO11, mediates DNA cleavage that forms the double-strand breaks (DSB) that initiate meiotic recombination. The complex promotes relaxation of negative and positive supercoiled DNA and DNA decatenation through cleavage and ligation cycles.

Gene Name: chromosome 11 open reading frame 80

Alternative Symbols: HYDM4, TOP6BL, TOPOVIBL

Protein Name: Type 2 DNA topoisomerase 6 subunit B-like

Molecular Weight: 53 kDa

Gene ID: 79703

UniProt: Q8N6T0