C11ORF80 antibody (C-Term)

Catalog No. ABIN5518072

The Rabbit Polyclonal anti-C11ORF80 antibody is suitable to detect C11ORF80 in samples from Human. It has been validated for WB.

Quick Overview for C11ORF80 antibody (C-Term) (ABIN5518072)

Target: C11ORF80 (Chromosome 11 Open Reading Frame 80 (C11ORF80))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C11ORF80 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-C11ORF80 Antibody

Binding Specificity: C-Term

Sequence: KVFREITQHQ FLHHCSCEVK QLTLEKKDSA QGTEDAPDNS SLELLADTSG

Predicted Reactivity: Human: 100%, Rat: 83%

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human C11ORF80

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for C11ORF80

Target: C11ORF80 (Chromosome 11 Open Reading Frame 80 (C11ORF80))

Alternative Name: C11ORF80

Background: Isoform 3: Component of a topoisomerase 6 complex specifically required for meiotic recombination. Together with SPO11, mediates DNA cleavage that forms the double-strand breaks (DSB) that initiate meiotic recombination. The complex promotes relaxation of negative and positive supercoiled DNA and DNA decatenation through cleavage and ligation cycles.

Alias Symbols: TOP6BL, TOPOVIBL

Protein Interaction Partner: UBC,

Protein Size: 485

Gene ID: 79703