CIRH1A antibody (Middle Region)

Catalog No. ABIN5518102

The Rabbit Polyclonal anti-CIRH1A antibody is suitable to detect CIRH1A in samples from Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse and Rabbit. It has been validated for WB.

Quick Overview for CIRH1A antibody (Middle Region) (ABIN5518102)

Target: CIRH1A (Cirrhosis, Autosomal Recessive 1A (Cirhin) (CIRH1A))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CIRH1A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CIRH1A Antibody

Binding Specificity: Middle Region

Purpose: UTP4 Antibody - middle region

Sequence: FAHHLELWRL GSTVATGKNG DTLPLSKNAD HLLHLKTKGP ENIICSCISP

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against CIR1A. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen for Anti-CIRH1A antibody is: synthetic peptide directed towards the Middle region of Human CIR1A

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP60683-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for CIRH1A

Target: CIRH1A (Cirrhosis, Autosomal Recessive 1A (Cirhin) (CIRH1A))

Alternative Name: UTP4

Background:

Background Information: This gene encodes a WD40-repeat-containing protein that is localized to the nucleolus. Mutation of this gene causes North American Indian childhood cirrhosis, a severe intrahepatic cholestasis that results in transient neonatal jaundice, and progresses to periportal fibrosis and cirrhosis in childhood and adolescence. Alternative splicing results in multiple transcript variants.

Gene Name: UTP4, small subunit processome component

Alternative Symbols: NAIC, CIRH1A, CIRHIN, TEX292

Protein Name: U3 small nucleolar RNA-associated protein 4 homolog

Molecular Weight: 68 kDa

Gene ID: 84916

UniProt: Q969X6