CCBL1 antibody (N-Term)

Catalog No. ABIN5518112

The Rabbit Polyclonal anti-CCBL1 antibody (ABIN5518112) specifically detects CCBL1 in WB. The antibody is reactive with Human samples.

Quick Overview for CCBL1 antibody (N-Term) (ABIN5518112)

Target: CCBL1 (Cysteine-S-conjugate beta-Lyase (CCBL1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCBL1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CCBL1 Antibody

Binding Specificity: N-Term

Purpose: KYAT1 Antibody - N-terminal region

Sequence: FDCYEPMTMM AGGRPVFVSL KPGPIQNGEL GSSSNWQLDP MELAGKFTSR

Characteristics: This is a rabbit polyclonal antibody against KAT1. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human KAT1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP75980-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for CCBL1

Target: CCBL1 (Cysteine-S-conjugate beta-Lyase (CCBL1))

Alternative Name: KYAT1

Background:

Background Information: This gene encodes a cytosolic enzyme that is responsible for the metabolism of cysteine conjugates of certain halogenated alkenes and alkanes. This metabolism can form reactive metabolites leading to nephrotoxicity and neurotoxicity. Increased levels of this enzyme have been linked to schizophrenia. Multiple transcript variants that encode different isoforms have been identified for this gene.

Gene Name: kynurenine aminotransferase 1

Alternative Symbols: GTK, KAT1, KATI, CCBL1

Protein Name: kynurenine--oxoglutarate transaminase 1

Molecular Weight: 46kDa

Gene ID: 883

NCBI Accession: NP_004050

UniProt: Q16773