CRP antibody (AA 20-225)

Catalog No. ABIN5518820

This anti-CRP antibody is a Rabbit Polyclonal antibody detecting CRP in WB, ELISA and IHC. Suitable for Rat and Mouse.

Quick Overview for CRP antibody (AA 20-225) (ABIN5518820)

Target: CRP (C-Reactive Protein (CRP))

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CRP antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-CRP Antibody

Binding Specificity: AA 20-225

Purpose: Anti-C Reactive Protein/Crp Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-C Reactive Protein/Crp Antibody Picoband® (ABIN5518820). Tested in ELISA, IHC, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived mouse Crp recombinant protein (Position: H20-S225). Mouse Crp shares 71.9% and 72.7% amino acid (aa) sequence identity with human and rat Crp, respectively.

Isotype: IgG

Application Details

Application Notes: Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
Western blot, 0.1-0.5 μg/mL, Rat, Mouse
1. Kilpatrick, J. M., Volanakis, J. E. : Molecular genetics, structure, and function of C-reactive protein. Immun. Res. 10: 43-53, 1991. 2. Kuta, A. E., Baum, L. L. : C-reactive protein is produced by a small number of normal human peripheral blood lymphocytes. J. Exp. Med. 164: 321-326, 1986. 3. Oliveira, E. B., Gotshlich, E. C., Liu, T. : Primary structure of human C-reactive protein. J. Biol. Chem. 254: 489-502, 1979.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Target Details for CRP

Target: CRP (C-Reactive Protein (CRP))

Alternative Name: Crp

Background:

Synonyms: C-reactive protein,Crp,Ptx1,

Tissue Specificity: Found in plasma.

Background: C Reactive Protein (CRP) is a major acute phase reactant synthesized primarily in the liver hepatocytes. It is composed of 5 identical, 21,500-molecular weight subunits. CRP mediates activities associated with preimmune nonspecific host resistance. CRP shows the strongest association with cardiovascular events. It is detectable on the surface of about 4 % of normal peripheral blood lymphocytes. Acute phase reactant CRP is produced in the liver.

Molecular Weight: 25 kDa

Gene ID: 12944

UniProt: P14847

Pathways: Carbohydrate Homeostasis