IGFBPI antibody (AA 69-259)

Catalog No. ABIN5518851

Product Details anti-IGFBPI Antibody

Target: IGFBPI (Insulin-Like Growth Factor Binding Protein 1 (IGFBPI))

Binding Specificity: AA 69-259

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IGFBPI antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Rabbit IgG polyclonal antibody for Insulin-like growth factor-binding protein 1(IGFBP1) detection. Tested with WB, IHC-P in Human.

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Insulin-like growth factor-binding protein 1(IGFBP1) detection. Tested with WB, IHC-P in Human.
Gene Name: insulin-like growth factor binding protein 1
Protein Name: Insulin-like growth factor-binding protein 1

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human IGFBP1 recombinant protein (Position: A69-N259). Human IGFBP1 shares 67.8% and 69.3% amino acid (aa) sequence identity with mouse and rat IGFBP1, respectively.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for IGFBPI

Target: IGFBPI (Insulin-Like Growth Factor Binding Protein 1 (IGFBPI))

Alternative Name: IGFBP1 (IGFBPI Products)

Synonyms: cb656 antibody, igfbp1 antibody, IGFBP-1 antibody, MGC68538 antibody, afbp antibody, ibp1 antibody, pp12 antibody, igf-bp25 antibody, higfbp-1 antibody, IGFBP1 antibody, LOC100223208 antibody, LOC100305121 antibody, AFBP antibody, IBP1 antibody, IGF-BP25 antibody, PP12 antibody, hIGFBP-1 antibody, IGFBA antibody, insulin like growth factor binding protein 1 antibody, insulin-like growth factor binding protein 1a antibody, insulin like growth factor binding protein 1 S homeolog antibody, insulin like growth factor binding protein 1 L homeolog antibody, insulin-like growth factor binding protein 1 antibody, IGFBP1 antibody, igfbp1a antibody, igfbp1.S antibody, igfbp1.L antibody, igfbp1 antibody, LOC100305121 antibody, Igfbp1 antibody

Background: IGFBP1, Insulin-like growth factor-binding protein 1, also known as placental protein 12 (PP12), is a protein that in humans is encoded by the IGFBP1 gene. The IGFBP1 gene has 4 exons and spans 5.9 kb. And the IGFBP1 gene is localized to 7p13-p12 by in situ hybridization. This gene is a member of the Insulin-like growth factor-binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a type-I thyroglobulin domain. The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Synonyms: Insulin-like growth factor-binding protein 1 | IBP-1 | IGF-binding protein 1 | IGFBP-1 | Igfbp1 | Igfbp-1 | P08833

Gene ID: 3484

UniProt: P08833

Pathways: Myometrial Relaxation and Contraction, ER-Nucleus Signaling, Growth Factor Binding