TMEM107 antibody (N-Term)

Catalog No. ABIN5518881

This Rabbit Polyclonal antibody specifically detects TMEM107 in WB, IHC and FACS. It exhibits reactivity toward Human.

Quick Overview for TMEM107 antibody (N-Term) (ABIN5518881)

Target: TMEM107 (Transmembrane Protein 107 (TMEM107))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TMEM107 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Product Details anti-TMEM107 Antibody

Binding Specificity: AA 22-57, N-Term

Purpose: Anti-TMEM107 Antibody Picoband®

Sequence: VITLFWSRDS NIQACLPLTF TPEEYDKQDI QLVAAL

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-TM Antibody Picoband® (ABIN5518881). Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human TMEM107, different from the related mouse and rat sequences by four amino acids.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL, Human
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
1. Christopher, K. J., Wang, B., Kong, Y., Weatherbee, S. D. Forward genetics uncovers transmembrane protein 107 as a novel factor required for ciliogenesis and Sonic hedgehog signaling. Dev. Biol. 368: 382-392, 2012. 2. Hartz, P. A. Personal Communication. Baltimore, Md. 1/12/2015.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Target Details for TMEM107

Target: TMEM107 (Transmembrane Protein 107 (TMEM107))

Alternative Name: TMEM107

Background:

Synonyms: Transmembrane protein 107,TMEM107,DC20, UNQ638/PRO1268,

Tissue Specificity: Ubiquitous. .

Background: Cilia are dynamic signaling organelles essential for developmental patterning, including left-right specification, skeletal formation, neural development, and organogenesis. TMEM107 is predicted to be critical for cilia formation and signaling in a subset of embryonic tissues. Based on an alignment of theTMEM107 sequence with the genomic sequence (GRCh38), the TMEM107 gene was mapped to chromosome 17p13.1.

Molecular Weight: 22 kDa

Gene ID: 84314