ATOH1 antibody (N-Term)

Catalog No. ABIN5518893

Product Details anti-ATOH1 Antibody

Target: ATOH1 (Atonal Homolog 1 (Drosophila) (ATOH1))

Binding Specificity: AA 1-30, N-Term

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATOH1 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for Protein atonal homolog 1(ATOH1) detection. Tested with WB in Human,Mouse,Rat.

Sequence: MSRLLHAEEW AEVKELGDHH RQPQPHHLPQ

Cross-Reactivity (Details): Predicted Cross Reactivity: human
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Characteristics: Rabbit IgG polyclonal antibody for Protein atonal homolog 1(ATOH1) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: atonal bHLH transcription factor 1
Protein Name: Protein atonal homolog 1

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human MATH1/HATH1 (1-30aa MSRLLHAEEWAEVKELGDHHRQPQPHHLPQ), different from the related mouse sequence by three amino acids.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse, Rat, Predicted Species: Human
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for ATOH1

Target: ATOH1 (Atonal Homolog 1 (Drosophila) (ATOH1))

Alternative Name: ATOH1 (ATOH1 Products)

Synonyms: Atoh1.1 antibody, ZATH-1 antibody, ath1 antibody, atoh1 antibody, zath1 antibody, zgc:136417 antibody, CATH1 antibody, Atoh1.2 antibody, Tath1 antibody, ATOH1 antibody, ATH1 antibody, HATH1 antibody, MATH-1 antibody, bHLHa14 antibody, Hath1 antibody, Math1 antibody, RGD1565171 antibody, atonal bHLH transcription factor 1a antibody, atonal homolog 1 (Drosophila) antibody, atonal bHLH transcription factor 1b antibody, absent MD neurons and olfactory sensilla antibody, atonal bHLH transcription factor 1 antibody, atoh1a antibody, ATOH1 antibody, atoh1b antibody, LOC663144 antibody, Atoh1 antibody

Background: Protein atonal homolog 1 is a protein that in humans is encoded by the ATOH1 gene. This protein belongs to the basic helix-loop-helix (BHLH) family of transcription factors. It activates E-box dependent transcription along with E47. ATOH1 is required for the formation of both neural and non-neural cell types. Using genetic deletion in mice, Atoh1 has been shown to be essential for formation of cerebellar granule neurons, inner ear hair cells, spinal cord interneurons, Merkel cells of the skin, and intestinal secretory cells (goblet, enteroendocrine, and Paneth cells).

Synonyms: Protein atonal homolog 1, Class A basic helix-loop-helix protein 14, bHLHa14, Helix-loop-helix protein hATH-1, hATH1, ATOH1, ATH1, BHLHA14, MATH 1, MATH1

Gene ID: 474

UniProt: Q92858