Epigen antibody (AA 23-110)

Catalog No. ABIN5518910

This anti-Epigen antibody is a Rabbit Polyclonal antibody detecting Epigen in WB. Suitable for Human and Rat.

Quick Overview for Epigen antibody (AA 23-110) (ABIN5518910)

Target: Epigen (EPGN) (Epithelial Mitogen (EPGN))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Epigen antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Epigen Antibody

Binding Specificity: AA 23-110

Purpose: Anti-Epigen/EPGN Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-Epigen/EPGN Antibody Picoband® (ABIN5518910). Tested in WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human Epigen recombinant protein (Position: A23-K110). Human Epigen shares 85.7% amino acid (aa) sequence identity with mouse Epigen.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL, Human, Rat
1. "Entrez Gene: Epithelial mitogen". 2. Schneider MR, Yarden Y (2014). "Structure and function of epigen, the last EGFR ligand". Semin. Cell Dev. Biol. 28: 57-61.

Comment:

We recommend Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Target Details for Epigen

Target: Epigen (EPGN) (Epithelial Mitogen (EPGN))

Alternative Name: EPGN

Background:

Synonyms: Epigen,Epithelial mitogen,EPG,EPGN,UNQ3072/PRO9904,

Background: Epigen, also known as epithelial mitogen, is a protein that in humans is encoded by the EPGN gene. The protein encoded by this gene is a member of the epidermal growth factor family. Members of this family are ligands for the epidermal growth factor receptor and play a role in cell survival, proliferation and migration. This protein has been reported to have high mitogenic activity but low affinity for its receptor. Expression of this transcript and protein have been reported in cancer specimens of the breast, bladder, and prostate.

Molecular Weight: 17 kDa

Gene ID: 255324

Pathways: RTK Signaling, EGFR Signaling Pathway