VEGFB antibody (AA 25-138)

Catalog No. ABIN5519073

This Rabbit Polyclonal antibody specifically detects VEGFB in WB and ELISA. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for VEGFB antibody (AA 25-138) (ABIN5519073)

Target: VEGFB (Vascular Endothelial Growth Factor B (VEGFB))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VEGFB antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-VEGFB Antibody

Binding Specificity: AA 25-138

Purpose: Anti-VEGFB Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-VEGFB Antibody Picoband® (ABIN5519073). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human VEGFB recombinant protein (Position: Q25-A138).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL
ELISA, 0.1-0.5 μg/mL
1. Gerace, L, Cirenei, N., Cappelletti, M., Petraroli, R., Sebastiani, F., Marziliano, N. Assignment of the mouse Vegfb gene to mouse chromosome 19B by in situ hybridization. Cytogenet. Cell Genet. 95: 242-243, 2001. 2. Silvestre, J.-S., Tamarat, R., Ebrahimian, T. G., Le-Roux, A., Clergue, M., Emmanuel, F., Duriez, M., Schwartz, B., Branellec, D., Levy, B. I. Vascular endothelial growth factor-B promotes in vivo angiogenesis. Circ. Res. 93: 114-123, 2003.

Comment:

We recommend Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Target Details for VEGFB

Target: VEGFB (Vascular Endothelial Growth Factor B (VEGFB))

Alternative Name: VEGFB

Background:

Synonyms: Vascular endothelial growth factor B, VEGF-B, VEGF-related factor, VRF, VEGFB, VRF,

Tissue Specificity: Expressed in all tissues except liver. Highest levels found in heart, skeletal muscle and pancreas.

Background: Vascular endothelial growth factor B also known as VEGF-B is a protein that, in humans, is encoded by the VEGF-B gene. VEGF-B is a growth factor that belongs to the vascular endothelial growth factor family, of which VEGF-A is the best-known member. In contrast to VEGF-A, VEGF-B plays a less pronounced role in the vascular system: Whereas VEGF-A is important for the formation of blood vessels, such as during development or in pathological conditions, VEGF-B seems to play a role only in the maintenance of newly formed blood vessels during pathological conditions. It also plays an important role on several types of neurons. And it is important for the protection of neurons in the retina and thecerebral cortex during stroke and of motoneurons during motor neuron diseases such as amyotrophic lateral sclerosis.

Molecular Weight: 29 kDa

Gene ID: 7423

Pathways: RTK Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals