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NG2 antibody

MCSP Reactivity: Human WB, IP, ICC, FACS Host: Mouse Monoclonal 7-1 unconjugated
Catalog No. ABIN5526901
  • Target See all NG2 (MCSP) Antibodies
    NG2 (MCSP) (Melanoma Associated Chondroitin Sulfate Proteoglycan (MCSP))
    Reactivity
    • 45
    • 23
    • 17
    • 1
    Human
    Host
    • 42
    • 14
    Mouse
    Clonality
    • 32
    • 23
    • 1
    Monoclonal
    Conjugate
    • 27
    • 10
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This NG2 antibody is un-conjugated
    Application
    • 30
    • 20
    • 10
    • 9
    • 8
    • 7
    • 7
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC), Flow Cytometry (FACS)
    Specificity
    The mouse monoclonal antibody 7.1 recognizes an extracellular epitope of NG2, the melanoma-associated chondroitin sulfate proteoglycan 4 of Mw approximately 220-300 kDa.
    Cross-Reactivity (Details)
    Human
    Purification
    Purified by protein-A affinity chromatography.
    Purity
    > 95 % (by SDS-PAGE)
    Immunogen
    Human bone marrow stromal cells infected with SV-40
    Clone
    7-1
    Isotype
    IgG1
    Top Product
    Discover our top product MCSP Primary Antibody
  • Application Notes
    Flow cytometry: Recommended dilution: 1-4 μg/mL.
    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Store at 2-8°C. Do not freeze.
  • Target
    NG2 (MCSP) (Melanoma Associated Chondroitin Sulfate Proteoglycan (MCSP))
    Alternative Name
    NG2 / Chondroitin sulfate proteoglycan 4 (MCSP Products)
    Synonyms
    HMW-MAA antibody, MCSP antibody, MCSPG antibody, MEL-CSPG antibody, MSK16 antibody, NG2 antibody, 4732461B14Rik antibody, AN2 antibody, Ng2 antibody, HSMCSGEN1 antibody, MCS antibody, chondroitin sulfate proteoglycan 4 antibody, sperm mitochondria associated cysteine rich protein antibody, CSPG4 antibody, Cspg4 antibody, SMCP antibody
    Background
    Chondroitin sulfate proteoglycan 4,NG2 / chondroitin sulfate proteoglycan 4 is expressed on glial cell populations, but not on normal hepatopoietic cells. It is an integral membrane chondroitin sulfate proteoglycan expressed by human malignant melanoma cells, where it plays role in stabilizing cell-substratum interactions during early events of melanoma cell spreading on endothelial basement membranes, and supports signaling pathways important for tumor invasion and growth. NG2 also serves as an AML blast tumor marker associated with poor prognosis.,Chondroitin sulfate proteoglycan 4, MSK16, CSPG4, MCSP
    Gene ID
    1464
    UniProt
    Q6UVK1
    Pathways
    Glycosaminoglycan Metabolic Process
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