Goldenhar Syndrome antibody (C-Term)

Catalog No. ABIN5530174

The Rabbit Polyclonal anti-Goldenhar Syndrome antibody (ABIN5530174) specifically detects Goldenhar Syndrome in IHC (p) and WB. The antibody is reactive with Human and Mouse samples.

Quick Overview for Goldenhar Syndrome antibody (C-Term) (ABIN5530174)

Target: Goldenhar Syndrome (GHS)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)

Product Details anti-Goldenhar Syndrome Antibody

Binding Specificity: AA 326-357, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This GHSR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 326-357 amino acids from the C-terminal region of human GHSR.

Isotype: Ig Fraction

Application Details

Application Notes: For IHC-P starting dilution is: 1:50~100

For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.4 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for Goldenhar Syndrome

Target: Goldenhar Syndrome (GHS)

Alternative Name: GHS

Background: This gene encodes a member of the G-protein coupled receptor family. The encoded protein may play a role in energy homeostasis and regulation of body weight. Two identified transcript variants are expressed in several tissues and are evolutionary conserved in fish and swine. One transcript, 1a, excises an intron and encodes the functional protein, this protein is the receptor for the Ghrelin ligand and defines a neuroendocrine pathway for growth hormone release. The second transcript (1b) retains the intron and does not function as a receptor for Ghrelin, however, it may function to attenuate activity of isoform 1a. Mutations in this gene are associated with autosomal idiopathic short stature.

Molecular Weight: 41 kDa

Gene ID: 2693

UniProt: Q92847