GLP-2 antibody (AA 220-248)

Catalog No. ABIN5530201

Product Details anti-GLP-2 Antibody

Target: GLP-2 (Glucagon-like peptide 2 (GLP-2))

Binding Specificity: AA 220-248

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GLP-2 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This GLP2R antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 220-248 amino acids from the Central region of human GLP2R.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for GLP-2

Target: GLP-2 (Glucagon-like peptide 2 (GLP-2))

Alternative Name: GLP2 (GLP-2 Products)

Synonyms: GLP1 antibody, GLP2 antibody, GRPP antibody, GLP-1 antibody, Glu antibody, PPG antibody, glucagon antibody, GCG antibody, Gcg antibody

Background: The GLP2 receptor (GLP2R) is a G protein-coupled receptor superfamily member closely related to the glucagon receptor ans GLP1 receptor. Glucagon-like peptide-2 (GLP2) is a 33-amino acid proglucagon-derived peptide produced by intestinal enteroendocrine cells. Like glucagon-like peptide-1 (GLP1) and glucagon itself, it is derived from the proglucagon peptide encoded by the GCG gene. GLP2 stimulates intestinal growth and upregulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. Moreover, GLP2 prevents intestinal hypoplasia resulting from total parenteral nutrition. GLP2R, a G protein-coupled receptor superfamily member is expressed in the gut and closely related to the glucagon receptor (GCGR) and the receptor for GLP1 (GLP1R). [provided by RefSeq].

Molecular Weight: 63 kDa

Gene ID: 9340

UniProt: O95838