5HT1B Receptor antibody (AA 225-253)

Catalog No. ABIN5530220

This Rabbit Polyclonal antibody specifically detects 5HT1B Receptor in WB. It exhibits reactivity toward Human.

Quick Overview for 5HT1B Receptor antibody (AA 225-253) (ABIN5530220)

Target: 5HT1B Receptor (HTR1B) (Serotonin Receptor 1B (HTR1B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This 5HT1B Receptor antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-5HT1B Receptor Antibody

Binding Specificity: AA 225-253

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This HTR1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 225-253 amino acids from the Central region of human HTR1B.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for 5HT1B Receptor

Target: 5HT1B Receptor (HTR1B) (Serotonin Receptor 1B (HTR1B))

Alternative Name: HTR1B

Background: The neurotransmitter serotonin (5-hydroxytryptamine, 5-HT) exerts a wide variety of physiologic functions through a multiplicity of receptors and may be involved in human neuropsychiatric disorders such as anxiety, depression, or migraine. These receptors consist of several main groups subdivided into several distinct subtypes on the basis of their pharmacologic characteristics, coupling to intracellular second messengers, and distribution within the nervous system (Zifa and Fillion, 1992 [PubMed 1359584]). The serotonergic receptors belong to the multigene family of receptors coupled to guanine nucleotide-binding proteins.

Molecular Weight: 44 kDa

Gene ID: 3351

UniProt: P28222

Pathways: JAK-STAT Signaling, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Feeding Behaviour, S100 Proteins