CBX8 antibody (AA 161-189)

Catalog No. ABIN5530750

The Rabbit Polyclonal anti-CBX8 antibody (ABIN5530750) specifically detects CBX8 in WB. The antibody is reactive with Mouse samples.

Quick Overview for CBX8 antibody (AA 161-189) (ABIN5530750)

Target: CBX8 (Chromobox Homolog 8 (CBX8))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CBX8 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CBX8 Antibody

Binding Specificity: AA 161-189

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CBX8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 161-189 amino acids from the Central region of human CBX8.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.39 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for CBX8

Target: CBX8 (Chromobox Homolog 8 (CBX8))

Alternative Name: CBX8

Background: Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.

Molecular Weight: 43 kDa

Gene ID: 57332

UniProt: Q9HC52