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Gastrin-Releasing Peptide antibody (AA 123-152)

GRP Reactivity: Human WB, IHC (p), FACS Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN5530774
  • Target See all Gastrin-Releasing Peptide (GRP) Antibodies
    Gastrin-Releasing Peptide (GRP)
    Binding Specificity
    • 15
    • 15
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 123-152
    Reactivity
    • 49
    • 34
    • 12
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 69
    • 1
    Rabbit
    Clonality
    • 69
    • 1
    Polyclonal
    Conjugate
    • 26
    • 8
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    This Gastrin-Releasing Peptide antibody is un-conjugated
    Application
    • 26
    • 26
    • 22
    • 14
    • 8
    • 6
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This GRPR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 123-152 amino acids from the Central region of human GRPR.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product GRP Primary Antibody
  • Application Notes
    For WB starting dilution is: 1:1000

    For IHC-P starting dilution is: 1:50~100

    For FACS starting dilution is: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.47 mg/mL
    Buffer
    Supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    Gastrin-Releasing Peptide (GRP)
    Alternative Name
    GRP (GRP Products)
    Synonyms
    BLP antibody, GRP antibody, BN antibody, GRP-10 antibody, preproGRP antibody, proGRP antibody, gastrin releasing peptide antibody, Grp antibody, GRP antibody
    Background
    Gastrin-releasing peptide (GRP) regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation and is a potent mitogen for neoplastic tissues. The effects of GRP are mediated through the gastrin-releasing peptide receptor. This receptor is a glycosylated, 7-transmembrane G-protein coupled receptor that activates the phospholipase C signaling pathway. The receptor is aberrantly expressed in numerous cancers such as those of the lung, colon, and prostate. An individual with autism and multiple exostoses was found to have a balanced translocation between chromosome 8 and a chromosome X breakpoint located within the gastrin-releasing peptide receptor gene.
    Molecular Weight
    43 kDa
    Gene ID
    2925
    UniProt
    P30550
    Pathways
    Peptide Hormone Metabolism, Hormone Activity
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