E2F7 antibody (AA 591-619)
Quick Overview for E2F7 antibody (AA 591-619) (ABIN5531082)
Target
See all E2F7 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 591-619
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogen
- This E2F7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 591-619 amino acids from the Central region of human E2F7.
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Isotype
- Ig Fraction
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Application Notes
- For WB starting dilution is: 1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Supplied in PBS with 0.09 % (W/V) sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- E2F7 (E2F Transcription Factor 7 (E2F7))
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Alternative Name
- E2F7
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Background
- Along with E2F8, inhibitor of E2F-dependent transcription that is important for the control of the E2F1-TP53 apoptotic pathway. Directly represses E2F1 transcription (By similarity). Binds DNA independently of DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3'. Appears to regulate a subset of E2F-dependent genes whose products are required for normal cell cycle progession.
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Molecular Weight
- 100 kDa
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Gene ID
- 144455
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UniProt
- Q96AV8
Target
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