HOXB8 antibody (C-Term)

Catalog No. ABIN5531404

Product Details anti-HOXB8 Antibody

Target: HOXB8 (Homeobox B8 (HOXB8))

Binding Specificity: AA 215-243, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HOXB8 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This HOXB8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 215-243 amino acids from the C-terminal region of human HOXB8.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for HOXB8

Target: HOXB8 (Homeobox B8 (HOXB8))

Alternative Name: HOXB8 (HOXB8 Products)

Synonyms: HOX2 antibody, HOX2D antibody, Hox-2.4 antibody, Hox2r1a antibody, hoxa8 antibody, z-9 antibody, HBX antibody, HBX24 antibody, HOXB8 antibody, homeobox B8 antibody, homeobox protein Hox-B8 antibody, homeo box B8 antibody, homeobox B8b antibody, porcine homeobox antibody, HOXB8 antibody, Hoxb8 antibody, LOC785855 antibody, hoxb8b antibody, HOX-2.4 antibody

Background: This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with colorectal cancer. Mice that have had the murine ortholog of this gene knocked out exhibit an excessive pathologic grooming behavior. This behavior is similar to the behavior of humans suffering from the obsessive-compulsive spectrum disorder trichotillomania.

Molecular Weight: 28 kDa

Gene ID: 3218

UniProt: P17481