PYGM antibody (C-Term)

Catalog No. ABIN5531905

Product Details anti-PYGM Antibody

Target: PYGM (Phosphorylase, Glycogen, Muscle (PYGM))

Binding Specificity: AA 698-727, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PYGM antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogen: This PYGM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 698-727 amino acids from the C-terminal region of human PYGM.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for PYGM

Target: PYGM (Phosphorylase, Glycogen, Muscle (PYGM))

Alternative Name: PYGM (PYGM Products)

Synonyms: pygb antibody, im:7150327 antibody, zgc:110706 antibody, AI115133 antibody, PG antibody, Muscpho antibody, zgc:63642 antibody, phosphorylase, glycogen, muscle L homeolog antibody, glycogen phosphorylase, muscle associated antibody, phosphorylase, glycogen, muscle A antibody, glycogen phosphorylase, muscle form antibody, muscle glycogen phosphorylase antibody, phosphorylase, glycogen, muscle b antibody, pygm.L antibody, PYGM antibody, pygma antibody, THA_70 antibody, Pygm antibody, pygmb antibody

Background: PYGM catalyzes and regulates the breakdown of glycogen to glucose-1-phosphate. Defects in PYGM are the cause of glycogen storage disease type 5 (GSD5), also known as McArdle disease. GSD5 is a metabolic disorder resulting in myopathy characterized by exercise intolerance, cramps, muscle weakness and recurrent myoglobinuria.

Molecular Weight: 97 kDa

Gene ID: 5837

UniProt: P11217

Pathways: Cellular Glucan Metabolic Process