PCDHA4 antibody (C-Term)

Catalog No. ABIN5531976

The Rabbit Polyclonal anti-PCDHA4 antibody has been validated for WB. It is suitable to detect PCDHA4 in samples from Human.

Quick Overview for PCDHA4 antibody (C-Term) (ABIN5531976)

Target: PCDHA4 (Protocadherin alpha 4 (PCDHA4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCDHA4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PCDHA4 Antibody

Binding Specificity: AA 761-790, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PCDHA4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 761-790 amino acids from the C-terminal region of human PCDHA4.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for PCDHA4

Target: PCDHA4 (Protocadherin alpha 4 (PCDHA4))

Alternative Name: PCDHA4

Background: This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.

Molecular Weight: 102 kDa

Gene ID: 56144

UniProt: Q9UN74