RBM5 antibody (N-Term)
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- Target See all RBM5 Antibodies
- RBM5 (RNA Binding Motif Protein 5 (RBM5))
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Binding Specificity
- AA 18-46, N-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This RBM5 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This RBM5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 18-46 amino acids from the N-terminal region of human RBM5.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product RBM5 Primary Antibody
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- Application Notes
- For WB starting dilution is: 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Supplied in PBS with 0.09 % (W/V) sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- Target
- RBM5 (RNA Binding Motif Protein 5 (RBM5))
- Alternative Name
- RBM5 (RBM5 Products)
- Synonyms
- wu:fc25a08 antibody, wu:fe06f12 antibody, g15 antibody, h37 antibody, luca15 antibody, rbm5 antibody, rmb5 antibody, RBM5 antibody, G15 antibody, LUCA15 antibody, RMB5 antibody, D030069N10Rik antibody, RNA binding motif protein 5 antibody, RNA binding motif protein 5 S homeolog antibody, RNA binding motif protein 5 L homeolog antibody, rbm5 antibody, rbm5.S antibody, RBM5 antibody, rbm5.L antibody, Rbm5 antibody
- Background
- Component of the spliceosome A complex. Regulates alternative splicing of a number of mRNAs. May modulate splice site pairing after recruitment of the U1 and U2 snRNPs to the 5' and 3' splice sites of the intron. May both positively and negatively regulate aopotosis by regulating the alternative splicing of several genes involved in this process, including FAS and CASP2/caspase-2. In the case of FAS, promotes exclusion of exon 6 thereby producing a soluble form of FAS that inhibits apoptosis. In the case of CASP2/caspase-2, promotes exclusion of exon 9 thereby producing a catalytically active form of CASP2/Caspase-2 that induces apoptosis.
- Molecular Weight
- 92 kDa
- Gene ID
- 10181
- UniProt
- P52756
- Pathways
- Ribonucleoprotein Complex Subunit Organization
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