KSR2 antibody (C-Term)

Catalog No. ABIN5532609

The Rabbit Polyclonal anti-KSR2 antibody is suitable to detect KSR2 in samples from Human. It has been validated for WB, FACS and IHC (p).

Quick Overview for KSR2 antibody (C-Term) (ABIN5532609)

Target: KSR2 (Kinase Suppressor of Ras 2 (KSR2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KSR2 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-KSR2 Antibody

Binding Specificity: AA 603-638, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This KSR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 603-638 amino acids from the C-terminal region of human KSR2.

Isotype: Ig Fraction

Application Details

Application Notes: For IHC-P starting dilution is: 1:50~100

For WB starting dilution is: 1:1000

For FACS starting dilution is: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.39 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for KSR2

Target: KSR2 (Kinase Suppressor of Ras 2 (KSR2))

Alternative Name: KSR2

Background: Location-regulated scaffold connecting MEK to RAF. Blocks MAP3K8 kinase activity and MAP3K8-mediated signaling. Acts as a negative regulator of MAP3K3-mediated activation of ERK, JNK and NF-kappa-B pathways, inhibiting MAP3K3-mediated interleukin-8 production.

Molecular Weight: 108 kDa

Gene ID: 283455

UniProt: Q6VAB6