SSX4 antibody (AA 69-97)

Catalog No. ABIN5532728

This Rabbit Polyclonal antibody specifically detects SSX4 in WB. It exhibits reactivity toward Human.

Quick Overview for SSX4 antibody (AA 69-97) (ABIN5532728)

Target: SSX4 (Synovial Sarcoma, X Breakpoint 4 (SSX4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SSX4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SSX4 Antibody

Binding Specificity: AA 69-97

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SSX4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 69-97 amino acids from the Central region of human SSX4.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for SSX4

Target: SSX4 (Synovial Sarcoma, X Breakpoint 4 (SSX4))

Alternative Name: SSX4

Background: The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X,18) translocation characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. Chromosome Xp11 contains a segmental duplication resulting in two identical copies of synovial sarcoma, X breakpoint 4, SSX4 and SSX4B, in tail-to-tail orientation. This gene, SSX4B, represents the more centromeric copy. Two transcript variants encoding distinct isoforms have been identified for this gene.

Molecular Weight: 22 kDa

Gene ID: 548313, 6759

UniProt: O60224