TAO Kinase 2 antibody (AA 415-443)

Catalog No. ABIN5533001

This Rabbit Polyclonal antibody specifically detects TAO Kinase 2 in WB. It exhibits reactivity toward Human.

Quick Overview for TAO Kinase 2 antibody (AA 415-443) (ABIN5533001)

Target: TAO Kinase 2 (TAOK2)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TAO Kinase 2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TAO Kinase 2 Antibody

Binding Specificity: AA 415-443

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This Mouse Taok2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 415-443 amino acids from the Central region of mouse Taok2.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for TAO Kinase 2

Target: TAO Kinase 2 (TAOK2)

Alternative Name: Taok2

Background: Taok2 may play a role in apoptotic morphological changes. May affect microtubule organization and stability. May play a role in the osmotic stress-MAPK8 pathway. Activates the JNK MAP kinase pathway through the specific activation of the upstream MKK3 and MKK6 kinases. Prevents MAP3K7-mediated activation of IKKA, and thus NF-kappa-B activation. Phosphorylates itself, MBP, activated MAPK8 and tubulins (By similarity).

Molecular Weight: 139 kDa

Gene ID: 381921

UniProt: Q6ZQ29

Pathways: Cell-Cell Junction Organization