MED26 antibody (AA 191-220)

Catalog No. ABIN5533369

Product Details anti-MED26 Antibody

Target: MED26 (Mediator Complex Subunit 26 (MED26))

Binding Specificity: AA 191-220

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MED26 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This MED26 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 191-220 amino acids from the Central region of human MED26.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for MED26

Target: MED26 (Mediator Complex Subunit 26 (MED26))

Alternative Name: MED26 (MED26 Products)

Synonyms: med26 antibody, wu:fe06c07 antibody, wu:fi75a09 antibody, zgc:55993 antibody, CRSP7 antibody, CRSP70 antibody, 5730493L18Rik antibody, AI414941 antibody, AW495270 antibody, Crsp7 antibody, Slc35e1 antibody, crsp7 antibody, mediator of RNA polymerase II transcription subunit 26 antibody, cofactor required for Sp1 transcriptional activation, subunit 7 antibody, mediator complex subunit 26 antibody, mediator complex subunit 26 L homeolog antibody, LOC725023 antibody, crsp7 antibody, MED26 antibody, Med26 antibody, med26.L antibody

Background: The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors.

Molecular Weight: 65 kDa

Gene ID: 9441

UniProt: O95402

Pathways: Regulation of Lipid Metabolism by PPARalpha