BPNT1 antibody (C-Term)

Catalog No. ABIN5533621

The Rabbit Polyclonal anti-BPNT1 antibody (ABIN5533621) specifically detects BPNT1 in WB. The antibody is reactive with Human samples.

Quick Overview for BPNT1 antibody (C-Term) (ABIN5533621)

Target: BPNT1 (3'(2'), 5'-Bisphosphate Nucleotidase 1 (BPNT1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BPNT1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-BPNT1 Antibody

Binding Specificity: AA 277-305, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This BPNT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 277-305 amino acids from the C-terminal region of human BPNT1.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.35 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for BPNT1

Target: BPNT1 (3'(2'), 5'-Bisphosphate Nucleotidase 1 (BPNT1))

Alternative Name: BPNT1

Background: BPNT1, also called bisphosphate 3-prime-nucleotidase, or BPntase, is a member of a magnesium-dependent phosphomonoesterase family. Lithium, a major drug used to treat manic depression, acts as an uncompetitive inhibitor of BPntase. The predicted human protein is 92 % identical to mouse BPntase. BPntase's physiologic role in nucleotide metabolism may be regulated by inositol signaling pathways. The inhibition of human BPntase may account for lithium-induced nephrotoxicity.

Molecular Weight: 33 kDa

Gene ID: 10380

UniProt: O95861

Pathways: Inositol Metabolic Process