SIAH1 antibody (AA 92-120)

Catalog No. ABIN5534219

This Rabbit Polyclonal antibody specifically detects SIAH1 in WB. It exhibits reactivity toward Human.

Quick Overview for SIAH1 antibody (AA 92-120) (ABIN5534219)

Target: SIAH1 (E3 Ubiquitin-Protein Ligase SIAH1 (SIAH1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SIAH1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SIAH1 Antibody

Binding Specificity: AA 92-120

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SIAH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 92-120 amino acids from the Central region of human SIAH1.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for SIAH1

Target: SIAH1 (E3 Ubiquitin-Protein Ligase SIAH1 (SIAH1))

Alternative Name: SIAH1

Background: SIAH1 is a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized. [provided by RefSeq].

Molecular Weight: 31 kDa

Gene ID: 6477

UniProt: Q8IUQ4