TRH antibody (AA 209-238)

Catalog No. ABIN5535020

This Rabbit Polyclonal antibody specifically detects TRH in WB. It exhibits reactivity toward Human.

Quick Overview for TRH antibody (AA 209-238) (ABIN5535020)

Target: TRH (Thyrotropin-Releasing Hormone (TRH))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRH antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TRH Antibody

Binding Specificity: AA 209-238

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This TRHR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 209-238 amino acids from the Central region of human TRHR.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.35 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for TRH

Target: TRH (Thyrotropin-Releasing Hormone (TRH))

Alternative Name: TRH

Background: Thyrotropin-releasing hormone (TRH, MIM 275120), a small neuropeptide, is widely distributed throughout the central and peripheral nervous system as well as in extraneural tissues. The peptide is synthesized in the hypothalamus and transported by the portal vascular system to the anterior pituitary where it acts on thyrotropic and lactotropic cells to promote secretion of TSH and prolactin, respectively. Thyrotropin-releasing hormone receptor is a G protein-coupled receptor that activates the inositol phospholipid-calcium-protein kinase C transduction pathway upon the binding of TRH. The TRHR gene is expressed in the thyrotrope cells of the anterior pituitary.

Molecular Weight: 45 kDa

Gene ID: 7201

UniProt: P34981

Pathways: Positive Regulation of Peptide Hormone Secretion, Feeding Behaviour