Dematin antibody (AA 249-277)

Catalog No. ABIN5535159

Product Details anti-Dematin Antibody

Target: Dematin (EPB49) (erythrocyte Membrane Protein Band 4.9 (Dematin) (EPB49))

Binding Specificity: AA 249-277

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Dematin antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This EPB49 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 249-277 amino acids from the Central region of human EPB49.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for Dematin

Target: Dematin (EPB49) (erythrocyte Membrane Protein Band 4.9 (Dematin) (EPB49))

Alternative Name: EPB49 (EPB49 Products)

Synonyms: MGC80597 antibody, MGC108072 antibody, EPB49 antibody, DMT antibody, AI325486 antibody, Epb4.9 antibody, Epb49 antibody, dematin antibody, dematin actin binding protein L homeolog antibody, dematin actin binding protein antibody, dmtn.L antibody, DMTN antibody, dmtn antibody, Dmtn antibody

Background: Dematin, or EPB49, is an actin-bundling protein originally identified in the erythroid membrane skeleton. Its actin-bundling activity is abolished upon phosphorylation by cAMP-dependent protein kinase and is restored after dephosphorylation (Rana et al., 1993 [PubMed 8341682]).

Molecular Weight: 46 kDa

Gene ID: 2039

UniProt: Q08495

Pathways: Regulation of Actin Filament Polymerization