GUCA2B antibody (C-Term)

Catalog No. ABIN5535223

Product Details anti-GUCA2B Antibody

Target: GUCA2B (Guanylate Cyclase Activator 2B (Uroguanylin) (GUCA2B))

Binding Specificity: AA 69-97, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GUCA2B antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This GUCA2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 69-97 amino acids from the C-terminal region of human GUCA2B.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for GUCA2B

Target: GUCA2B (Guanylate Cyclase Activator 2B (Uroguanylin) (GUCA2B))

Alternative Name: GUCA2B (GUCA2B Products)

Synonyms: GUCA2B antibody, AV066530 antibody, Gcap2 antibody, Ugn antibody, GCAP-II antibody, UGN antibody, guanylate cyclase activator 2B antibody, guanylate cyclase activator 2b (retina) antibody, GUCA2B antibody, Guca2b antibody

Background: Uroguanylin and guanylin (GUCA2A, MIM 139392), peptide homologs of the bacterial heat-stable enterotoxins (e.g., the E. coli ST toxin, STa), are endogenous activators of the guanylate cyclase-2C receptor (GUCY2C, MIM 601330), which synthesizes cyclic GMP (cGMP), a key component of several intracellular signal transduction pathways.

Molecular Weight: 12 kDa

Gene ID: 2981

UniProt: Q16661