TTL antibody (C-Term)

Catalog No. ABIN5535730

Product Details anti-TTL Antibody

Target: TTL (Tubulin tyrosine Ligase (TTL))

Binding Specificity: AA 232-263, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TTL antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This TTL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 232-263 amino acids from the C-terminal region of human TTL.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.33 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for TTL

Target: TTL (Tubulin tyrosine Ligase (TTL))

Alternative Name: TTL (TTL Products)

Background: TTL is a cytosolic enzyme involved in the posttranslational modification of alpha-tubulin (see MIM 602529). Alpha-tubulin within assembled microtubules is detyrosinated over time at the C terminus. After microtubule disassembly, TTL restores the tyrosine residues and consequently participates in a cycle of tubulin detyrosination and tyrosination (Erck et al., 2003 [PubMed 14571137]).

Molecular Weight: 43 kDa

Gene ID: 150465

UniProt: Q8NG68

Pathways: Regulation of Cell Size