TTL antibody (C-Term)
Quick Overview for TTL antibody (C-Term) (ABIN5535730)
Target
See all TTL AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 232-263, C-Term
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogen
- This TTL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 232-263 amino acids from the C-terminal region of human TTL.
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Isotype
- Ig Fraction
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Application Notes
- For WB starting dilution is: 1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.33 mg/mL
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Buffer
- Supplied in PBS with 0.09 % (W/V) sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- TTL (Tubulin tyrosine Ligase (TTL))
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Alternative Name
- TTL
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Background
- TTL is a cytosolic enzyme involved in the posttranslational modification of alpha-tubulin (see MIM 602529). Alpha-tubulin within assembled microtubules is detyrosinated over time at the C terminus. After microtubule disassembly, TTL restores the tyrosine residues and consequently participates in a cycle of tubulin detyrosination and tyrosination (Erck et al., 2003 [PubMed 14571137]).
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Molecular Weight
- 43 kDa
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Gene ID
- 150465
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UniProt
- Q8NG68
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Pathways
- Regulation of Cell Size
Target
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