ERN1 antibody (C-Term)
Quick Overview for ERN1 antibody (C-Term) (ABIN5536062)
Target
See all ERN1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 827-855, C-Term
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogen
- This Mouse Ern1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 827-855 amino acids from the C-terminal region of mouse Ern1.
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Isotype
- Ig Fraction
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anti-Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1) (AA 401-500) antibody
ERN1 Reactivity: Human WB, ELISA, IF, PLA Host: Mouse Monoclonal 8D12 unconjugated
anti-Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1) (AA 401-500) antibodyERN1 Reactivity: Human WB, ELISA, IHC (p) Host: Mouse Monoclonal 3D1 unconjugated
anti-Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1) (AA 282-433) antibodyERN1 Reactivity: Human WB, ELISA, IHC Host: Mouse Monoclonal 9F2 unconjugated
anti-Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1) (AA 252-260) antibodyERN1 Reactivity: Human, Mouse, Rat, Pig WB, ELISA, FACS, IF (cc), IF (p), ICC, IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1) (pSer726) antibodyERN1 Reactivity: Human, Mouse, Rat WB, ELISA, FACS, IF (cc), IF (p), ICC, IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1) (pSer724) antibodyERN1 Reactivity: Human WB, ELISA, IF Host: Rabbit Monoclonal 1F12 unconjugated Recombinant Antibody
anti-Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1) (pSer724) antibodyERN1 Reactivity: Human WB, FACS Host: Rabbit Monoclonal 24GB5220 unconjugated Recombinant Antibody
anti-Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1) (Internal Region) antibodyVerified ERN1 Reactivity: Human WB, ELISA, FACS Host: Goat Polyclonal unconjugated
anti-Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1) (C-Term) antibodyERN1 Reactivity: Human, Mouse, Rat WB, IF, EIA Host: Rabbit Polyclonal unconjugated
anti-Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1) (AA 493-561) antibodyERN1 Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated
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Application Notes
- For WB starting dilution is: 1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Supplied in PBS with 0.09 % (W/V) sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- ERN1 (Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1))
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Alternative Name
- Ern1
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Background
- Ern1 senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto-activation. The active endoribonuclease domain splices XBP1 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator and triggering growth arrest and apoptosis.
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Molecular Weight
- 110 kDa
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Gene ID
- 78943
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UniProt
- Q9EQY0
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Pathways
- ER-Nucleus Signaling, Unfolded Protein Response
Target
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