GLRB antibody (N-Term)
-
- Target See all GLRB Antibodies
- GLRB (Glycine Receptor, beta (GLRB))
-
Binding Specificity
- AA 103-132, N-Term
-
Reactivity
- Human
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This GLRB antibody is un-conjugated
-
Application
- Western Blotting (WB)
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This GLRB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 103-132 amino acids from the N-terminal region of human GLRB.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product GLRB Primary Antibody
-
-
- Application Notes
- For WB starting dilution is: 1:1000
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Supplied in PBS with 0.09 % (W/V) sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
-
- Target
- GLRB (Glycine Receptor, beta (GLRB))
- Alternative Name
- GLRB (GLRB Products)
- Synonyms
- HKPX2 antibody, glrb antibody, MGC145156 antibody, AI853901 antibody, Glyrb antibody, spa antibody, spastic antibody, glrb2 antibody, zgc:101041 antibody, glycine receptor beta antibody, glycine receptor, beta antibody, glycine receptor, beta subunit antibody, glycine receptor, beta b antibody, GLRB antibody, Glrb antibody, glrb antibody, glrbb antibody
- Background
- This gene encodes the beta subunit of the glycine receptor, which is a pentamer composed of alpha and beta subunits. The receptor functions as a neurotransmitter-gated ion channel, which produces hyperpolarization via increased chloride conductance due to the binding of glycine to the receptor. Mutations in this gene cause startle disease, also known as hereditary hyperekplexia or congenital stiff-person syndrome, a disease characterized by muscular rigidity. Alternative splicing results in multiple transcript variants.
- Molecular Weight
- 56 kDa
- Gene ID
- 2743
- UniProt
- P48167
-