MED6 antibody (AA 135-164)
Quick Overview for MED6 antibody (AA 135-164) (ABIN5537170)
Target
See all MED6 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 135-164
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogen
- This MED6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 135-164 amino acids from the Central region of human MED6.
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Isotype
- Ig Fraction
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Application Notes
- For WB starting dilution is: 1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Supplied in PBS with 0.09 % (W/V) sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- MED6 (Mediator Complex Subunit 6 (MED6))
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Alternative Name
- MED6
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Background
- Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
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Molecular Weight
- 28 kDa
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Gene ID
- 10001
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UniProt
- O75586
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Pathways
- Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha
Target
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