PNPLA6 antibody (C-Term)

Catalog No. ABIN5537393

This Rabbit Polyclonal antibody specifically detects PNPLA6 in WB. It exhibits reactivity toward Human.

Quick Overview for PNPLA6 antibody (C-Term) (ABIN5537393)

Target: PNPLA6 (Patatin-Like phospholipase Domain Containing 6 (PNPLA6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PNPLA6 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PNPLA6 Antibody

Binding Specificity: AA 1000-1029, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PNPLA6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1000-1029 amino acids from the C-terminal region of human PNPLA6.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for PNPLA6

Target: PNPLA6 (Patatin-Like phospholipase Domain Containing 6 (PNPLA6))

Alternative Name: PNPLA6

Background: PNPLA6 is a phospholipase that deacetylates intracellular phosphatidylcholine to produce glycerophosphocholine. It is thought to function in neurite outgrowth and process elongation during neuronal differentiation. The protein is anchored to the cytoplasmic face of the endoplasmic reticulum in both neurons and non-neuronal cells. Mutations in this gene result in autosomal recessive spastic paraplegia, and the protein is the target for neurodegeneration induced by organophosphorus compounds and chemical warfare agents. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].

Molecular Weight: 150 kDa

Gene ID: 10908

UniProt: Q8IY17

Pathways: Ribonucleoside Biosynthetic Process