ZAP70 antibody (C-Term)

Catalog No. ABIN5537404

The Rabbit Polyclonal anti-ZAP70 antibody (ABIN5537404) specifically detects ZAP70 in WB. The antibody is reactive with Human and Mouse samples.

Quick Overview for ZAP70 antibody (C-Term) (ABIN5537404)

Target: ZAP70 (zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZAP70 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ZAP70 Antibody

Binding Specificity: AA 530-558, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This Mouse Zap70 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 530-558 amino acids from the C-terminal region of mouse Zap70.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for ZAP70

Target: ZAP70 (zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70))

Alternative Name: Zap70

Background: Plays a role in T-cell development and lymphocyte activation. Essential for TCR-mediated IL-2 production. Isoform 1 induces TCR-mediated signal transduction, isoform 2 does not.

Molecular Weight: 70 kDa

Gene ID: 22637

UniProt: P43404

Pathways: TCR Signaling, Ubiquitin Proteasome Pathway