PDE8A antibody (AA 557-587)

Catalog No. ABIN5537478

The Rabbit Polyclonal anti-PDE8A antibody is suitable to detect PDE8A in samples from Human. It has been validated for WB and IHC (p).

Quick Overview for PDE8A antibody (AA 557-587) (ABIN5537478)

Target: PDE8A (phosphodiesterase 8A (PDE8A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDE8A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-PDE8A Antibody

Binding Specificity: AA 557-587

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogen: This PDE8A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 557-587 amino acids from the Central region of human PDE8A.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for PDE8A

Target: PDE8A (phosphodiesterase 8A (PDE8A))

Alternative Name: PDE8A

Background: PDE8A plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This phosphodiesterase, which has a high affinity for cAMP, may be involved in maintaining basal levels of the cyclic nucleotide and/or in the cAMP regulation of germ cell development.

Molecular Weight: 93 kDa

Gene ID: 5151

UniProt: O60658

Pathways: cAMP Metabolic Process