SAP18 antibody (AA 58-86)

Catalog No. ABIN5537590

This anti-SAP18 antibody is a Rabbit Polyclonal antibody detecting SAP18 in WB. Suitable for Human.

Quick Overview for SAP18 antibody (AA 58-86) (ABIN5537590)

Target: SAP18 (Sin3A-Associated Protein, 18kDa (SAP18))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SAP18 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SAP18 Antibody

Binding Specificity: AA 58-86

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SAP18 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 58-86 amino acids from the Central region of human SAP18.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for SAP18

Target: SAP18 (Sin3A-Associated Protein, 18kDa (SAP18))

Alternative Name: SAP18

Background: Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by this gene is a component of the histone deacetylase complex, which includes SIN3, SAP30, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This protein directly interacts with SIN3 and enhances SIN3-mediated transcriptional repression when tethered to the promoter. A pseudogene has been identified on chromosome 2.

Molecular Weight: 18 kDa

Gene ID: 10284

UniProt: O00422