SPG20 antibody (C-Term)
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- Target See all SPG20 Antibodies
- SPG20 (Spastic Paraplegia 20 (Troyer Syndrome) (SPG20))
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Binding Specificity
- AA 491-519, C-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SPG20 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This SPG20 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 491-519 amino acids from the C-terminal region of human SPG20.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product SPG20 Primary Antibody
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- Application Notes
- For WB starting dilution is: 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Supplied in PBS with 0.09 % (W/V) sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- Target
- SPG20 (Spastic Paraplegia 20 (Troyer Syndrome) (SPG20))
- Alternative Name
- SPG20 (SPG20 Products)
- Synonyms
- SPARTIN antibody, TAHCCP1 antibody, AI840044 antibody, C79168 antibody, mKIAA0610 antibody, spartin antibody, Spg20 antibody, spg20a antibody, zgc:172059 antibody, spg20b antibody, zgc:153766 antibody, spartin antibody, spastic paraplegia 20, spartin (Troyer syndrome) homolog (human) antibody, spartin a antibody, spartin b antibody, SPART antibody, Spg20 antibody, Spart antibody, sparta antibody, spartb antibody
- Background
- SPG20 is a protein containing a MIT (Microtubule Interacting and Trafficking molecule) domain, and is implicated in regulating endosomal trafficking and mitochondria function. The protein localizes to mitochondria and partially co-localizes with microtubules. Stimulation with epidermal growth factor (EGF) results in protein translocation to the plasma membrane, and the protein functions in the degradation and intracellular trafficking of EGF receptor. Multiple alternatively spliced variants, encoding the same protein, have been identified. Mutations associated with this gene cause autosomal recessive spastic paraplegia 20 (Troyer syndrome).
- Molecular Weight
- 73 kDa
- Gene ID
- 23111
- UniProt
- Q8N0X7
- Pathways
- Regulation of Cell Size, SARS-CoV-2 Protein Interactome
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