AKR1D1 antibody (AA 111-139)

Catalog No. ABIN5538440

Product Details anti-AKR1D1 Antibody

Target: AKR1D1 (Aldo-Keto Reductase Family 1, Member D1 (AKR1D1))

Binding Specificity: AA 111-139

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AKR1D1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This AKR1D1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 111-139 amino acids from the Central region of human AKR1D1.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for AKR1D1

Target: AKR1D1 (Aldo-Keto Reductase Family 1, Member D1 (AKR1D1))

Alternative Name: AKR1D1 (AKR1D1 Products)

Synonyms: 3o5bred antibody, CBAS2 antibody, SRD5B1 antibody, 3-oxo-5-beta-steroid 4-dehydrogenase-like antibody, aldo-keto reductase family 1 member D1 antibody, aldo-keto reductase family 1, member D1 antibody, aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase) antibody, LOC491379 antibody, AKR1D1 antibody, Akr1d1 antibody

Background: The enzyme encoded by this gene is responsible for the catalysis of the 5-beta-reduction of bile acid intermediates and steroid hormones carrying a delta(4)-3-one structure. Deficiency of this enzyme may contribute to hepatic dysfunction. Three transcript variants encoding different isoforms have been found for this gene. Other variants may be present, but their full-length natures have not been determined yet.

Molecular Weight: 37 kDa

Gene ID: 6718

UniProt: P51857

Pathways: Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process, Monocarboxylic Acid Catabolic Process