SH3PXD2A antibody (N-Term)

Catalog No. ABIN5538765

The Rabbit Polyclonal anti-SH3PXD2A antibody is suitable to detect SH3PXD2A in samples from Human. It has been validated for WB.

Quick Overview for SH3PXD2A antibody (N-Term) (ABIN5538765)

Target: SH3PXD2A (SH3 and PX Domains 2A (SH3PXD2A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SH3PXD2A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SH3PXD2A Antibody

Binding Specificity: AA 222-250, N-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SH3PXD2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 222-250 amino acids from the N-terminal region of human SH3PXD2A.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for SH3PXD2A

Target: SH3PXD2A (SH3 and PX Domains 2A (SH3PXD2A))

Alternative Name: SH3PXD2A

Background: SH3PXD2A is required for podosome formation, degradation of the extracellular matrix, and for the invasiveness of some cancer cells. Binds phosphatidylinositol 3-phosphate (PtdIns(3)P) and phosphatidylinositol 3,4-biphosphate (PtdIns(3,4)P2). In association with ADAM12, mediates the neurotoxic effect of beta-amyloid peptide.

Molecular Weight: 125 kDa

Gene ID: 9644

UniProt: Q5TCZ1