VEGF1 antibody (N-Term)

Catalog No. ABIN5539309

This anti-VEGF1 antibody is a Rabbit Polyclonal antibody detecting VEGF1 in WB. Suitable for Human.

Quick Overview for VEGF1 antibody (N-Term) (ABIN5539309)

Target: VEGF1 (PVF1) (PDGF and VEGF-Related Factor 1 (PVF1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VEGF1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-VEGF1 Antibody

Binding Specificity: AA 66-95, N-Term

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogen: This VEGF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 66-95 amino acids from the N-terminal region of human VEGF1.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for VEGF1

Target: VEGF1 (PVF1) (PDGF and VEGF-Related Factor 1 (PVF1))

Alternative Name: VEGF1

Background: VEGF1 is a member of the PDGF/VEGF growth factor family and and is often found as a disulfide linked homodimer. This protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Elevated levels of this protein are linked to POEMS syndrome, also known as Crow-Fukase syndrome. Mutations in VEGF1 have been associated with proliferative and nonproliferative diabetic retinopathy.

Molecular Weight: 27 kDa

Gene ID: 7422

UniProt: P15692