ACPP antibody

Catalog No. ABIN5539951

The Mouse Monoclonal anti-ACPP antibody (Clone LT-3D1) (ABIN5539951) specifically detects ACPP in FACS, EIA and ELISA (Detection). The antibody is reactive with Human samples.

Quick Overview for ACPP antibody (ABIN5539951)

Target: ACPP (Acid Phosphatase, Prostate (ACPP))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ACPP antibody is un-conjugated

Application: Flow Cytometry (FACS), Enzyme Immunoassay (EIA), ELISA (Detection)

Clone: LT-3D1

Product Details anti-ACPP Antibody

Specificity: Recognizes Prostatic Acid Phosphatase PAP (PAcP, ACPP).

Purification: Affinity Chromatography on Protein G

Immunogen: Genetic immunisation with cDNA encoding Human PAP.

Isotype: IgG1

Application Details

Application Notes: Flow cytometry: 1.2 μg/10e6 cells. Cell based ELISA with intakt, transiently transfected cells: 1/200-1/400. ELISA (detection): With clone LT-6C11-A1 as capture antibody.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Phosphate buffered saline, pH 7.2

Storage: 4 °C,-20 °C

Storage Comment: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for ACPP

Target: ACPP (Acid Phosphatase, Prostate (ACPP))

Alternative Name: acpp,prostatic acid phosphatase

Background: Human prostatic acid phosphatase (PAP) is a non-specific phosphomonoesterase, synthesised and secreted into seminal plasma under androgenic control. Human PAP is a 100 kDa glycoprotein containing two subunits of approximately 50 kDa each (1,2). It catalyses the dephosphorylation of organic monophosphate esters, demonstrating optimum activity at an acid pH . Produced by the prostatic epithelium, serum levels of PAP are very low in healthy individuals, but are often elevated in malignant and benign prostatic disease while it has been used as a marker of diagnosis and therapy control of cancer of the prostate gland (3).

UniProt: P15309

Pathways: Synaptic Membrane, Ribonucleoside Biosynthetic Process