BMP2 antibody (AA 283-396)

Catalog No. ABIN5540049

The Mouse Monoclonal anti-BMP2 antibody has been validated for WB, ICC, IF and EIA. It is suitable to detect BMP2 in samples from Human.

Quick Overview for BMP2 antibody (AA 283-396) (ABIN5540049)

Target: BMP2 (Bone Morphogenetic Protein 2 (BMP2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This BMP2 antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Clone: AT15B3

Product Details anti-BMP2 Antibody

Binding Specificity: AA 283-396

Purification: Protein-A affinity chromatography

Immunogen: Recombinant human BMP2 (283-396aa) purified from E. coli

Isotype: IgG2b

Application Details

Application Notes: ELISA. Immunocytochemistry/Immunofluorescence. Western blot / Immunoblot. The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution is 1:1000.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4 containing 0.02 % Sodium Azide and 10 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for BMP2

Target: BMP2 (Bone Morphogenetic Protein 2 (BMP2))

Alternative Name: bmp2,bmp2a

Background: BMP-2 (Bone morphogenetic protein 2) is multi-functional growth factors that belong to the transforming growth factor beta (TGF beta) superfamily. It plays an important role in embryonic dorsal-ventral patterning, organogenesis, limb bud formation, and bone formation and regeneration. BMP-2 also promotes the maintenance and repair of colonic epithelium, suppresses neuronal dopamine synthesis and release, induces apoptosis in medulloblastoma cells, and is required for cardiac contractility.

UniProt: P12643

Pathways: Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Muscle Cell Differentiation, Growth Factor Binding, Positive Regulation of fat Cell Differentiation