CCR1
Reactivity: Human
WB
Host: Rabbit
Polyclonal
RB52859
unconjugated
Application Notes
ELISA: Reacts with the CCR1 peptide KLH conjugate (Immunogen) in indirect ELISA assay.
Restrictions
For Research Use only
Buffer
0.01M PBS, pH 7.0
Storage
4 °C,-20 °C
Storage Comment
Prior to reconstitution store at 2-8°C. Following reconstitution store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Expiry Date
12 months
Target
CCR1
(Chemokine (C-C Motif) Receptor 1 (CCR1))
Alternative Name
cd191,ccr1
Background
CCR1, also called CD191, is the first CC chemokine receptor identified at DNA level. Like other CC chemokine receptors, CCR1 is a G-protein coupled 7 transmembrane protein. Genes for CCR1 and several other chemokine forms a cluster on chromosome 3p. A number of CC chemokines, such as MIP-1β, Rentes, MIP1- α , MIP1- δ , RANTES, and MIP3, MIP1 γ, HCC1 and HCC4 have been found to be the ligands of CCR1. CCR1 expression has been reported to be implicated in rheumatoid arthritis, chronic lymphocytic leukemia and hairy cell leukemia.