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Thrombomodulin antibody

This anti-Thrombomodulin antibody is a Mouse Monoclonal antibody detecting Thrombomodulin in EIA. Suitable for Human.
Catalog No. ABIN5540104

Quick Overview for Thrombomodulin antibody (ABIN5540104)

Target

See all Thrombomodulin (THBD) Antibodies
Thrombomodulin (THBD)

Reactivity

  • 130
  • 39
  • 22
  • 4
  • 4
  • 2
  • 1
Human

Host

  • 77
  • 73
  • 6
  • 2
  • 2
Mouse

Clonality

  • 92
  • 67
  • 1
Monoclonal

Conjugate

  • 79
  • 21
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Thrombomodulin antibody is un-conjugated

Application

  • 102
  • 77
  • 48
  • 44
  • 29
  • 29
  • 26
  • 22
  • 21
  • 14
  • 14
  • 12
  • 12
  • 5
  • 5
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
Enzyme Immunoassay (EIA)

Clone

B-S24
  • Specificity

    Recognises Thrombomodulin (TM), a 105 kDa protein.

    Purification

    Ion Exchange Chromatography

    Immunogen

    Eahy 926 cell lines.

    Isotype

    IgG1
  • Application Notes

    ELISA.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    0.22 μm Sterile-filtered PBS. Carrier and preservative free.

    Preservative

    Azide free

    Storage

    4 °C

    Storage Comment

    Store undiluted at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch.

    Expiry Date

    12 months
  • Target

    Thrombomodulin (THBD)

    Alternative Name

    cd141,thbd

    Background

    CD141/Thrombomodulin is an exclusively endothelial cell surface glycoprotein that forms a 1:1 complex with thrombin. Binding of thrombin to this high-affinity receptor alters its specificity toward several substrates. The complex activates protein C approximately 1000 times faster than thrombin alone. Activated protein C degrades clotting factors V and VIII thus, thrombomodulin converts thrombin into a physiologic anticoagulant. Thrombomodulin is also found in the circulatory and urinary systems, the physiologic significance of this is obscure.

    UniProt

    P07204
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