Chromogranin A antibody

Catalog No. ABIN5540207

This Mouse Monoclonal antibody specifically detects Chromogranin A in FACS and EIA. It exhibits reactivity toward Human and Mouse.

Quick Overview for Chromogranin A antibody (ABIN5540207)

Target: Chromogranin A (CHGA)

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This Chromogranin A antibody is un-conjugated

Application: Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Clone: NJ-5C9

Product Details anti-Chromogranin A Antibody

Specificity: Recognizes Chromogranin A (CGA).

Purification: Affinity Chromatography on Protein G.

Immunogen: Genetic immunisation with cDNA encoding CGA

Isotype: IgG1

Application Details

Application Notes: Flow cytometry: 1.2 μg/10e6 cells. ELISA: 1/200-1/400. Cell based ELISA with intakt, transiently transfected cells: 1/200-1/400.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Phosphate buffered saline, pH 7.2

Storage: 4 °C,-20 °C

Storage Comment: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for Chromogranin A

Target: Chromogranin A (CHGA)

Alternative Name: chromogranin a

Background: Chromogranin A (CgA) is a 49 kDa protein which is a member of the granin/secretogranin family of acidic glycoproteins. It is specifically expressed in all endocrine and neuroendocrine cells and plays multiple roles in the process of regulated secretion of peptide hormones and neurotransmitters (1). Owing to its over-expression in several tumors of neuroendocrine origin, CgA is of diagnostic value in classical endocrine, in hormone-negative and in neuroendocrine tumors (2).

UniProt: P10645

Pathways: Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling