CACYBP antibody (AA 1-185)

Catalog No. ABIN5540232

The Mouse Monoclonal anti-CACYBP antibody is suitable to detect CACYBP in samples from Human. It has been validated for WB and EIA.

Quick Overview for CACYBP antibody (AA 1-185) (ABIN5540232)

Target: CACYBP (Calcyclin Binding Protein (CACYBP))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CACYBP antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Clone: AT3G8

Product Details anti-CACYBP Antibody

Binding Specificity: AA 1-185

Purification: Protein-A affinity chromatography

Immunogen: Recombinant human CACYBP (1-185aa) purified from E. coli.

Isotype: IgG2a

Application Details

Application Notes: The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution is 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4 containing 0.02 % Sodium Azide and 10 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for CACYBP

Target: CACYBP (Calcyclin Binding Protein (CACYBP))

Alternative Name: cacybp

Background: CACYBP (Calcyclin-binding protein) is primarily a nuclear protein that contains one CS domain and one SGS domain. CACYBP is believed to be involved in calcium-dependent ubiquitination and subsequent proteosomal degradation of target proteins. It most likely serves as a molecular bridge in ubiquitin E3 complexes. It also participates in the ubiquitin-mediated degradation of b-catenin. CACYBP is thought to be a potential inhibitor of cell growth and invasion in the gastric cancer cell through its effects on b-catenin protein expression and transcriptional activation of TCF/LEF.

UniProt: Q9HB71

Pathways: Response to Growth Hormone Stimulus